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Characterization of Loss-Of-Function KCNJ2 Mutations in Atypical Andersen Tawil Syndrome

Characterization of Loss-Of-Function KCNJ2 Mutations in Atypical Andersen Tawil Syndrome

July 2, 2025 Category: Blog

Andersen-Tawil Syndrome (ATS) is a rare disease defined by the association of cardiac arrhythmias, periodic paralysis and dysmorphic features, and is caused by KCNJ2 loss-of-function mutations.However, when extracardiac symptoms are atypical or absent, the patient can be diagnosed with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT), a

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Study on driver model for hybrid truck based on driving simulator experimental results

July 2, 2025 Category: Blog

In this paper, a proposed car-following driver model taking into account some features of both the compensatory and anticipatory model representing the human pedal operation has been verified by driving simulator experiments with several real drivers.The comparison between computer simulations performed by determined model parameters with the exper

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Multiscale modeling of viscoelastic behavior of unidirectional composite laminates and deployable structures

July 2, 2025 Category: Blog

Due to Still Life Art the inherent viscoelasticity of constituent matrix and the possibility of long-term storage, space deployable structures made of composites are likely to exhibit relaxation in the stored strain energy, which may degrade their deployment performance.This paper presents a bottom-up finite element based multiscale computational s

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Influence of Different Water Depths on Gas Jet of Underwater Scarfed Nozzle

July 2, 2025 Category: Blog

Thrust vector control by scarfed nozzle jet can realize attitude control and trajectory adjustment of the undersea vehicle and improve the maneuvering performance and stability of the undersea vehicle.In order to investigate the working state of the Patio Umbrella Package underwater scarfed nozzle, the Reynolds time-averaged Navier-Stokes(RANS) met

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Functional analysis of Girardia tigrina transcriptome seeds pipeline for anthelmintic target discovery

July 2, 2025 Category: Blog

Abstract Background Neglected diseases caused by helminth infections impose a massive hindrance to progress in the developing world.While basic research on parasitic flatworms (platyhelminths) continues to expand, researchers have yet to broadly adopt a free-living model to complement the study of these important parasites.Methods We report the hig

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